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Nanoparticles and human health: live cell imaging of uptake and trafficking of nanoparticles (SiO2, TiO2, ZnO, CeO, Pt etc.) in endothelial cells in an artificial blood circulation model and toxicity measurements


Strobel C., Torrano A.A., Herrmann R., Malissek M., Bräuchle C., Reller A., Treuel L., Hilger I.
Effects of the physicochemical properties of titanium dioxide nanoparticles, commonly used as sun protection agents, on microvascular endothelial cells
J. Nanopart. Res. (2014), DOI 10.1007/s11051-013-2130-3

Torrano A.A., Blechinger J., Bräuchle C.
Trafficking and Intracellular Distribution of Nanoparticles (Subchapter 6.4 of Chapter 6: "Biological Responses to Nanomaterials")
In: "Safety Aspects of Engineered Nanomaterials"
Eds.: Luther W., Zweck A.
Pan Stanford Publishing 2013, p. 175

Torrano A.A., Blechinger J., Osseforth C., Argyo C., Reller A., Bein T., Michaelis J., Bräuchle C.
A fast analysis method to quantify nanoparticle uptake on a single cell level
Nanomedicine 8(11) (2013), 1815.

Blechinger J., Bauer A.T., de Andrade Torrano A., Gorzelanny C., Bräuchle C., Schneider S.W.
Uptake Kinetics and Nanotoxicity of Silica Nanoparticles are Cell Type Dependent
Small 9(23)(2013), 3970.
Inside cover picture for Small December 2013, 9(23)

Lebold T., Schloßbauer A., Schneider K., Schermelleh L., Leonhardt H., Bein T.*, Bräuchle C.*
Controlling the mobility of oligonucleotides in the nanochannels of mesoporous silica
Advanced Functional Materials 22(1) (2012), 106.
Cover picture for Advanced Functional Materials (January 2012, 22(1)

Blechinger J., Herrmann R., Kiener D., Garcia-Garcia F., Scheu C., Reller A., Bräuchle C.
Perylene-labeled Silica Nanoparticles: Synthesis and Characterization of Three Novel Silica Nanoparticle Species for Live Cell Imaging
Small 6(21), (2010), 2427.

Katayama Y., Burkacky O., Meyer M., Bräuchle C., Gratton E., Lamb D.C.
Real-time Nanomicroscopy via Three-Dimensional Single-Particle Tracking
ChemPhysChem 10(14) (2009), 2458.

 
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Ludwig-Maximilians-
Universität München
Department Chemie
Physikalische Chemie I
Butenandtstr. 11
Gerhard-Ertl-Gebäude
D-81377 München
 
Phone: +49-89-2180-77547
Mail: Prof. C. Braeuchle
 
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News

October 2017

New publication: Dendrimer-Based Signal Amplification of Click-Labelled DNA in Situ, ChemBioChem 18, (2017), 1716. more information... 

New publication: Quantification of volume and lipid filling of intracellular vesicles carrying the ABCA3 transporter, BBA - Molecular Cell Research, 1864(12) (2017), 2330. more information... 

New publication: Spektromikroskopie für biologische Fragestellungen in der Physikalischen Chemie, p. 85, Beitrag im Buch “Unendliche Weiten: Kreuz und quer durchs Chemie-Universum”, Eds.: T.K. Lindhorst, H-J.Quadbeck-Seeger, Gesellschaft Deutscher Chemiker Wiley VCH Verlag GmbH (2017). more information... 

New publication: New insights into the intracellular distribution pattern of cationic amphiphilic drugs, Scientific Reports (2017), Article number 44277. more information... 

New publication: Azido pentoses: A New Tool to Efficiently Label Mycobacterium tuberculosis Clinical Isolates, ChemBioChem 18 (2017), 1172. more information... 

New publication: The Endothelial Glycocalyx Controls Interactions of Quantum Dots with the Endothelium and Their Translocation across the Blood−Tissue Border ACS Nano, 11(2), (2017), 1498. more information... 

New publication: The Glycocalyx Regulates the Uptake of Nanoparticles by Human Endothelial Cells In Vitro, Nanomedicine 12(3) (2017), 207.  more information... 

New publication: Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases, Oncotarget 7(31) (2016), 50461. more information... 

New publication: En route from artificial to natural: Evaluation of inhibitors of mannose-specific adhesion of E. coli under flow , Biochimica et Biophysica Acta 1860 (2016), 2031. more information... 

New publication: Cell Membrane Penetration and Mitochondrial Targeting by Platinum-Decorated Ceria Nanoparticles, Nanoscale 8 (2016), 13352. more information... 

New publication: Dendronized Mesoporous Silica Nanoparticles Provide an Internal Endosomal Escape Mechanism for Successful Cytosolic Drug Release, Microporous and Mesoporous Materials 227 (2016), 242. more information... 

New publication: Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release, Nanoscale (2016), 8101. more information... 

 

New publication: Highly efficient siRNA delivery from core–shell mesoporous silica nanoparticles with multifunctional polymer caps, Nanoscale 8 (2016), 4007. more information... 

 

New publication: Artificial Formation and Tuning of Glycoprotein Networks on Live Cell Membranes: A Single-Molecule Tracking Study, ChemPhysChem 17(6) (2016), 829. more information... 

 

New publication: Switching first contact: photocontrol of E. coli adhesion to human cells, Chem. Comm. 52 (2016), 1254. more information... 

Dendrimer-Based Signal Amplification of Click-Labelled DNA in Situ

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